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Pharmacokinetics of intravenously administered desmosine in sheep
Connective Tissue Research
|January 1, 1984
Abstract:
The pharmacokinetics of desmosine following a 5 mg intravenous dose was determined in five sheep. The biological half-life (t 1/2 beta) of desmosine varied between 81-489 min. Urinary recovery of unchanged desmosine indicated that the compound is not extensively metabolized and that the primary route of elimination is via the kidney.