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[Heterotopic smooth muscle in the choroid]
Klinische Monatsblatter Fur Augenheilkunde
|September 1, 1983
Summary
Smooth muscle found in the choroid of both eyes is a rare, isolated malformation. This finding may explain the occurrence of rare choroidal leiomyomas in otherwise healthy eyes.
Area of Science:
- Ophthalmology
- Pathology
- Histology
Background:
- Mycosis fungoides is a type of cutaneous T-cell lymphoma affecting the skin.
- Ocular adnexa involvement, including eyelids, conjunctiva, and sclera, can occur in mycosis fungoides.
Observation:
- A histological and ultrastructural examination of a deceased patient's eyes revealed an unexpected finding: smooth muscle tissue within the choroid of both eyes.
- This smooth muscle was observed in globes where the eyelids, conjunctiva, and sclera were affected by mycosis fungoides.
- The surrounding ocular tissues, apart from the smooth muscle, appeared non-dysplastic.
Findings:
- The presence of smooth muscle in the choroid is interpreted as a congenital anomaly, or malformation, rather than a neoplastic process.
- This heterotopic smooth muscle represents a previously undocumented finding in ocular pathology.
Implications:
- This case suggests that such rare heterotopias of smooth muscle in the choroid could be the underlying developmental basis for the occurrence of choroidal leiomyomas.
- Further research into these malformations may elucidate the pathogenesis of rare ocular smooth muscle tumors.