Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Case report--zomepirac suicide.

R C Backer, V H Kshirsagar, I M Sopher

Journal of Analytical Toxicology

|September 1, 1983

Summary

This summary is machine-generated.

This case study details a fatal zomepirac sodium overdose. Postmortem blood levels of zomepirac were 152 mg/L, indicating a significant drug concentration at the time of death.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Validation of a standardised gait score to predict the healing of tibial fractures.

The Journal of bone and joint surgery. British volume·2012

Same author

Drug screening with EMIT reagents: a quantitative approach to quality control.

Clinical chemistry·1991

Same author

Carisoprodol concentrations from different anatomical sites: three overdose cases.

Journal of analytical toxicology·1990

Same author

Fatal unintended carbon monoxide poisoning in West Virginia from nonvehicular sources.

American journal of public health·1989

Same author

Fatality resulting from cyclizine overdose.

Journal of analytical toxicology·1989

Same author

Unintentional deaths from carbon monoxide in motor vehicle exhaust: West Virginia.

American journal of public health·1989

Same journal

Theory put into practice: probabilistic approach to propranolol as the cause of death.

Journal of analytical toxicology·2026

Same journal

Is drug facilitated sexual assault changing? About a case involving 4-bromomethcathinone.

Journal of analytical toxicology·2026

Same journal

Differentiation of 2-, 3-, and 4-Fluorofuranylfentanyl Using HPLC-MS and Human Liver Microsomes.

Journal of analytical toxicology·2026

Same journal

Trends and Circumstances of Pediatric Fentanyl Deaths in North Carolina: A 10-year Retrospective Study.

Journal of analytical toxicology·2026

Same journal

Drug Detection in Traffic-Related Fatalities in Connecticut (2020-2024).

Journal of analytical toxicology·2026

Same journal

Characterization of postmortem γ-hydroxybutyric acid (GHB) and a novel model to discern exogenous use.

Journal of analytical toxicology·2026

See all related articles

Area of Science:

Forensic toxicology
Pharmacology
Analytical chemistry

Background:

Zomepirac sodium, a nonsteroidal anti-inflammatory drug (NSAID), has been associated with serious adverse events.
Understanding drug concentrations in fatal cases is crucial for toxicological assessments.

Observation:

A case of suicidal death involving zomepirac sodium is presented.
Antemortem blood specimen showed a zomepirac concentration of 286 mg/L, nine hours before death.
Postmortem blood concentration of zomepirac was determined to be 152 mg/L.

Findings:

Quantitation of zomepirac was performed using an ultraviolet spectrophotometer.
Confirmation of zomepirac presence was achieved through gas chromatography.
The study documents the drug levels in a fatal overdose scenario.

Related Experiment Videos

Implications:

This case highlights the potential toxicity of zomepirac sodium at elevated concentrations.
Accurate analytical methods are essential for forensic investigations involving drug-related deaths.
The findings contribute to the toxicological database for zomepirac and its role in fatal outcomes.