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Related Experiment Videos

The "empty sella" in childhood.

D C Costigan, D Daneman, D Harwood-Nash

    Clinical Pediatrics
    |August 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Empty sella (ES) in children is rare and presents differently than in adults. This study highlights unique childhood ES associations and increased endocrine/visual issues.

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    Area of Science:

    • Pediatric Endocrinology
    • Neuroimaging
    • Rare Diseases

    Background:

    • The

    Observation:

    • Four pediatric cases of empty sella (ES) were identified, revealing novel associations.
    • These cases included central precocious puberty, secondary ES from prolactinoma treatment, and pseudotumor cerebri.
    • One case presented with no significant pathology.

    Findings:

    • Pediatric ES (27 reported cases) shows distinct features from adult ES, including a lack of female preponderance.
    • Higher frequencies of secondary ES, endocrine abnormalities (67%), and visual disturbances (47%) are observed in children.
    • Seven pediatric cases exhibited local skull dysplasia and/or familial inheritance patterns.

    Implications:

    Related Experiment Videos

    • Understanding these pediatric ES variations is crucial for accurate diagnosis and management.
    • Further research is needed to elucidate the specific mechanisms and long-term outcomes of childhood ES.
    • This study expands the known spectrum of empty sella presentations in pediatric populations.