Clinical features and prognosis in Fuchs' uveitis syndrome

Fuchs' uveitis syndrome has a characteristic clinical appearance but is frequently overlooked when heterochromia is subtle or absent. In this series of 54 patients, additional features of this syndrome are described, including absent or reversed heterochromia, occasional peripheral anterior synechia, spontaneous hyphema, rubeosis, venous sheathing, and corneal edema. Cataracts and glaucoma were more frequent and associated with a poorer prognosis than previously reported. Topical applications of corticosteroids are occasionally useful, but the patients later become refractory.