[Chances of abortion prophylaxis in early pregnancy (author's transl)]

7870 pregnancies during the years 1964-1970 observed in a cooperative clinical study give the data basis of an exploratory statistical analysis. Here the associations of drugs taken during the first three months of pregnancy with the incidence of early spontaneous abortions before the fifth month are demonstrated. The rates are corrected for time of enrollment. Women having taken antiemetic drugs or preparations containing vitamins or minerals have less abortions than women without intake of these drugs. This is found especially in the presence of early nausea or vomiting and of bleedings in the first trimenon. It is important that these drugs have not been used for the treatment of bleedings. Therefore the takers and the non-takers are comparable. A success of the then usual treatment with female sexual hormones could not be found. The high abortion rates of women treated with tranquilizers cannot be interpreted as a failure of this treatment because of the epidemiological non-experimental character of the study.