[Immune response in a nonfatal staphylococcal infection in guinea pigs]

The model of nonlethal staphylococcal infection in guinea pigs was used to demonstrate that at an early period after inoculation chemotaxis of neutrophiles enhanced only in response to the specific antigen, the percentage of phagocytes with receptors for IgG increased, while immune phagocytosis by receptors for IgM decreased; at a later period the decrease of phagocytosis by receptors for IgG occurred. Besides, at a later period after inoculation a slight decrease in the total T-lymphocyte population and at an early period the increase of the content of TG were observed. The dynamics of lymphocytes with receptors for staphylococci was subject to cyclic fluctuations.