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[Cellular reactions of increased delayed sensitivity in human pseudotuberculosis]
Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|January 1, 1982
Summary
Far Eastern scarlatiniform fever triggers a specific cellular immunity transformation, manifesting as a delayed-type hypersensitivity reaction. Immunological tests accurately diagnose this condition, proving specific, sensitive, and simple for clinical use.
Area of Science:
- Immunology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Far Eastern scarlatiniform fever is a distinct febrile illness.
- Understanding the immune response is crucial for diagnosis and management.
- Previous diagnostic methods may lack specificity or sensitivity.
Purpose of the Study:
- To investigate the cellular immunity system's response in patients with Far Eastern scarlatiniform fever.
- To evaluate the diagnostic utility of specific immunological tests for this condition.
Main Methods:
- Utilized Fradkin's neutrophil damage test, capillary cell migration inhibition test, and intradermal testing.
- Examined 145 patients with Far Eastern scarlatiniform fever, 99 healthy controls, and 54 patients with other diseases.
Main Results:
- Demonstrated a specific transformation in the cellular immunity system associated with Far Eastern scarlatiniform fever.
- Identified this transformation as a delayed-type hypersensitivity reaction.
- Confirmed the specificity and high sensitivity of the employed immunological tests.
Conclusions:
- Far Eastern scarlatiniform fever induces a characteristic delayed-type hypersensitivity response.
- The tested immunological methods are effective, specific, sensitive, and simple for diagnosing Far Eastern scarlatiniform fever.