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[Atrophic rhinitis in swine]
Veterinarno-Meditsinski Nauki
|January 1, 1978
Summary
Experimental Bordetella bronchiseptica infection in pigs caused severe nasal lesions. A combined prophylaxis and treatment approach, particularly with borgal, shows promise for managing these respiratory conditions.
Area of Science:
- Veterinary Pathology
- Bacteriology
Context:
- Bordetella bronchiseptica is a significant pathogen in swine respiratory disease.
- Understanding the pathological effects of B. bronchiseptica is crucial for effective disease management.
Purpose:
- To investigate the clinical and morphological outcomes of experimental Bordetella bronchiseptica infection in pigs.
- To compare experimental infections with naturally occurring respiratory disease in swine.
Summary:
- Pigs experimentally infected with Bordetella bronchiseptica developed severe dystrophic and necrotic changes in nasal mucosa, cartilage, and bone.
- Spontaneously affected pigs harbored Pasteurella multocida, Pseudomonas aeruginosa, and Mycoplasma, but not B. bronchiseptica.
- Basophilic inclusion bodies were observed in the epithelial cells of tubulous glands in naturally infected pigs.
Impact:
- Findings suggest Bordetella bronchiseptica causes significant nasal pathology in pigs.
- A combined prophylaxis and treatment strategy is recommended.
- The drug borgal demonstrated promising therapeutic potential for these conditions.