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Extramedullary hematopoiesis simulating parasagittal meningioma
Summary
Polycythemia vera with myeloid metaplasia can cause intracranial masses mimicking tumors. This case highlights extramedullary hematopoiesis in the falx cerebri as a rare cause of raised intracranial pressure.
Area of Science:
- Neurology
- Hematology
- Oncology
Background:
- Polycythemia vera and myeloid metaplasia are myeloproliferative neoplasms.
- These conditions can lead to extramedullary hematopoiesis (EMH).
Observation:
- A patient with a nine-year history of polycythemia vera and myeloid metaplasia presented with symptoms of raised intracranial pressure.
- Imaging revealed a mass obliterating the sagittal fissure, clinically and radiologically resembling a meningioma.
Findings:
- Biopsy confirmed the mass was extramedullary hematopoiesis involving the falx cerebri.
- This represents an uncommon manifestation of myeloproliferative disease.
Implications:
- Extramedullary hematopoiesis should be considered in the differential diagnosis of intracranial masses in patients with myeloproliferative neoplasms.
- This case underscores the diverse clinical presentations of myeloproliferative diseases, which can mimic primary intracranial tumors.