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[Effect of lymphocytes on macrophage phagocytic activity in delayed hypersensitivity to Staphylococcus]
The direct contact of macrophages with lymphocytes enhanced the functional activity of macrophages: the phagocytosis rate increased from 53.5% to 92.7%, the phagocytosis index increased from 8.7 to 15.7. Splenic lymphocytes obtained from mice with delayed hypersensitivity to staphylococci, when stimulated with staphylococcal corpuscular antigen in vitro, released lymphokines into the culture fluid. These lymphokines enhanced the capacity of macrophages and lymphocytes for mutual contacts.
The direct contact of macrophages with lymphocytes enhanced the functional activity of macrophages: the phagocytosis rate increased from 53.5% to 92.7%, the phagocytosis index increased from 8.7 to 15.7. Splenic lymphocytes obtained from mice with delayed hypersensitivity to staphylococci, when stimulated with staphylococcal corpuscular antigen in vitro, released lymphokines into the culture fluid. These lymphokines enhanced the capacity of macrophages and lymphocytes for mutual contacts.