Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal function abnormalities induced by marathon running

J A Neviackas, J H Bauer

    Southern Medical Journal
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Chemiluminescent Probes for Imaging H<sub>2</sub>S in Living Animals.

    Chemical science·2015
    Same author

    THE TETANUS BACILLUS AS AN INTESTINAL SAPROPHYTE IN MAN.

    The Journal of experimental medicine·2009
    Same author

    STUDIES ON THE RELATION OF TETANUS BACILLI IN THE DIGESTIVE TRACT TO TETANUS ANTITOXIN IN THE BLOOD.

    The Journal of experimental medicine·2009
    Same author

    THE IMMUNITY PRODUCED BY THE GROWTH OF TETANUS BACILLI IN THE DIGESTIVE TRACT.

    The Journal of experimental medicine·2009
    Same author

    THE INCUBATION PERIOD OF YELLOW FEVER IN THE MOSQUITO.

    The Journal of experimental medicine·2009
    Same author

    ULTRAFILTRATION OF THE VIRUS OF POLIOMYELITIS.

    The Journal of experimental medicine·2009
    Same journal

    SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

    Southern medical journal·2026
    Same journal

    Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

    Southern medical journal·2026
    Same journal

    Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

    Southern medical journal·2026
    Same journal

    Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

    Southern medical journal·2026
    Same journal

    Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

    Southern medical journal·2026
    Same journal

    Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

    Southern medical journal·2026
    See all related articles

    Marathon running can impair kidney function, especially in warm weather. Runners experienced abnormal urinalysis and reduced inulin clearance, with effects dependent on race temperature.

    Area of Science:

    • Nephrology
    • Exercise Physiology
    • Environmental Medicine

    Background:

    • Marathon racing is a strenuous endurance event.
    • Potential impacts of marathon running on renal function are not fully understood.
    • Environmental factors like temperature may influence physiological responses.

    Purpose of the Study:

    • To evaluate changes in renal function in asymptomatic runners after marathon races.
    • To investigate the influence of ambient temperature (warm vs. cold) on these renal changes.
    • To assess the recovery of renal function one week post-marathon.

    Main Methods:

    • Study included asymptomatic runners participating in warm and cold weather marathons (42 km).
    • Measurements included serum electrolytes, creatine phosphokinase (CPK), urinalysis, urinary myoglobin, and renal function tests (para-aminohippurate [PAH] and inulin clearances).

    Related Experiment Videos

  • Assessments were conducted pre-race, 6 hours post-race, and 1 week post-race.

    • Main Results:

    • Post-race, CPK levels were higher in warm weather runners; urinalysis was abnormal in all runners.
    • Urinary myoglobin was detected post-race in warm weather runners only.
    • Warm weather runners showed a 50% decrease in inulin clearance post-race, while cold weather runners had no significant change in renal function tests.

    Conclusions:

    • Marathon running induces renal function abnormalities in asymptomatic runners.
    • The severity of these renal function abnormalities is dependent on ambient temperature.
    • Kidney function generally recovers by one week, but temperature-related differences persist.