Hyperplastic Gastropathy. Analysis of 50 selected cases from 1955-1980

Hyperplastic gastropathy remains a rare condition. Fifty cases of hyperplastic gastropathy (adhering to rigid pathologic and clinical criteria) were analyzed from the English literature for the past 25 years. This was compared to a similar review of 50 cases published 25 years ago. A clearer pathologic classification-mucous cell hyperplasia, glandular cell hyperplasia and mixed mucous-glandular cell hyperplasia is recommended. The etiology and pathogenesis remain obscure. The clinical characteristics and medical and surgical therapy are discussed. The course appears uncertain as does the relationship to gastric carcinoma.