[Utilization of minicomputer for the quality control of radioimmunoassay (author's transl)]

In our nuclear medicine laboratory the quality control (QC) of radioimmunoassay (RIA) has been performed along the line of WHO program for standardization and quality control of RIA. The QC procedure was automated using a minicomputer in order to avoid tedious and time-consuming hand processing. The program was written with BASIC language. The counts of radioactivity measured in autowell counters are regarded in PTR, through which the data are read into a minicomputer (Scintipac 200). After informations on the concentrations of standards are registered through keyboard of CRT, the data processing is performed including curve fitting, dose calculation and quality control. As the indicators for QC response error relationship (RER), standard curve, precision profile and QC chart are displayed on CRT. On the basis of rejection criteria using these indicators, bad assays are identified to be omitted from reporting. The subroutine installed in the minicomputer system is used for the storage of data on QC samples in each assay, which are used for construction of QC charts. The use of a minicomputer enables implementation of QC of RIA on routine basis with ease and speed.