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[Allergologic studies of intolerance to rosin]
Dermatosen in Beruf Und Umwelt. Occupation and Environment
|January 1, 1980
Summary
Colophony allergy varies among individuals. Some patients react to abietylic alcohol but not abietic acid, while methylabietate in plasters can cause allergic reactions.
Area of Science:
- Allergy and immunology
- Dermatology
- Contact dermatitis
Background:
- Colophony (resin) is a known contact allergen.
- Individual allergic responses to colophony components can differ significantly.
Purpose of the Study:
- To investigate the specific allergologic profiles of individuals allergic to colophony.
- To assess the allergenicity of colophony components, including methylabietate in adhesives.
Main Methods:
- Patch testing was performed on 13 individuals with a known colophony allergy.
- Specific colophony derivatives, including abietylic alcohol and abietic acid, were used.
- The allergenicity of methylabietate in sticking plasters was evaluated in 12 cases.
Main Results:
- Patch tests revealed diverse allergic reactions to colophony components.
- Some patients showed sensitivity exclusively to abietylic alcohol.
- Others did not react to abietic acid.
- Methylabietate, a plasticizer in plasters, induced allergic reactions in 6 out of 12 subjects.
Conclusions:
- Colophony allergy is characterized by varied individual responses to its constituents.
- Abietylic alcohol and abietic acid present different allergenic potentials.
- Methylabietate in "hypoallergenic" plasters can be a significant allergen, necessitating careful formulation consideration.