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The humoral response to an allograft
I V Hutchinson1, Y Alam, W R Ayliffe
1School of Biological Sciences, University of Manchester Medical School, UK.
Eye (London, England)
|January 1, 1995
Abstract:
Antibodies are known to damage grafted tissues by a variety of means, so it is important to know how the humoral response is initiated. In this paper we summarise the cellular events in B cell activation, the mechanisms of antibody-mediated rejection and the evidence that antibody apparently does not contribute to early corneal graft rejection. The role of antibodies in chronic graft loss is discussed.