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Renal aspergilloma due to Aspergillus flavus
Z U Khan1, G Gopalakrishnan, K al-Awadi
1Department of Microbiology, Faculty of Medicine, Kuwait University.
Summary
This rare case highlights Aspergillus flavus causing renal aspergilloma in a patient with urinary schistosomiasis. Prompt diagnosis via urine microscopy and successful treatment with liposomal amphotericin B are crucial.
Area of Science:
- Mycology
- Urology
- Infectious Diseases
Background:
- Renal aspergillomas are infrequently documented fungal infections.
- Urinary tract fungal colonization can occur, particularly in specific patient populations.
- Concomitant infections, like schistosomiasis, may predispose to fungal overgrowth.
Observation:
- A rare case of Aspergillus flavus colonization involving the renal pelvis and upper ureter is presented.
- The patient had coexisting urinary schistosomiasis.
- Diagnostic methods included direct microscopy of urine showing fungal hyphae and fungal culture.
Findings:
- Microscopic examination of urine revealed characteristic fungal hyphae.
- Culture successfully isolated Aspergillus flavus.
- The patient received successful treatment with liposomal amphotericin B.
Implications:
- Direct microscopic examination of urine is vital for diagnosing urogenital fungal infections.
- Renal aspergilloma must be considered in the differential diagnosis of urinary tract filling defects.
- Immunocompromised individuals with urinary abnormalities are at higher risk.