Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Split cord malformations

M S Dias1, D Pang

  • 1Department of Pediatric Neurosurgery, Children's Hospital of Buffalo, New York, USA.

Neurosurgery Clinics of North America
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Obesity, diabetes and their metabolic correlates in middle-aged adults with Down syndrome.

Journal of intellectual disability research : JIDR·2023
Same author

Calcium pyruvate in the attenuation of the water deficit on the agro-industrial quality of ratoon sugarcane.

Brazilian journal of biology = Revista brasleira de biologia·2023
Same author

A single infusion of intravenous lidocaine for primary headaches and trigeminal neuralgia: a retrospective analysis.

Frontiers in neurology·2023
Same author

Mineral composition and production of guava under salt stress and salicylic acid.

Brazilian journal of biology = Revista brasleira de biologia·2023
Same author

Pyruvic acid as attenuator of water deficit in cotton plants varying the phenological stage.

Brazilian journal of biology = Revista brasleira de biologia·2023
Same author

Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same journal

Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Spinal Cord Deformities Associated with Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Radiation Therapy for Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Treatment Strategies of Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Vascular Lesions of the Spinal Cord: Arteriovenous and Cavernous Malformations.

Neurosurgery clinics of North America·2026
Same journal

Hemangioblastomas of the Spinal Cord.

Neurosurgery clinics of North America·2026
See all related articles

This study proposes a new classification for split cord malformations (SCMs), dividing them into two types based on dural coverings. This unifying approach aims to improve understanding and guide early surgical intervention for spinal cord tethering.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Orthopedic Surgery

Background:

  • Existing classifications for split cord malformations (SCMs), including diastematomyelia and diplomyelia, lack clarity and a unified understanding.
  • SCMs are congenital anomalies characterized by the division of the spinal cord, often leading to progressive neurological deficits.

Purpose of the Study:

  • To propose a unifying classification for split cord malformations (SCMs) based on a common embryogenesis.
  • To differentiate SCMs into two distinct types to better understand their pathology and guide treatment.

Main Methods:

  • Review and re-evaluation of previous classifications of SCMs.
  • Development of a new classification system based on the embryological origins and anatomical features of SCMs.

Related Experiment Videos

  • Categorization of SCMs into Type I (two dural sacs with a spur) and Type II (single dural sac with fibrous bands).

    • Main Results:

    • The proposed classification divides SCMs into Type I and Type II based on dural sac composition and intervening mesenchymal tissue.
    • Type I SCMs feature two dural sacs separated by a bony or fibrocartilaginous spur.
    • Type II SCMs involve a single dural sac with intradural fibrous bands.

    Conclusions:

    • The proposed unifying classification provides a clearer framework for understanding SCMs and their shared embryogenesis.
    • Both types of SCMs involve mesenchymal elements that can cause progressive spinal cord tethering, leading to neurological, urological, and orthopedic deterioration.
    • Early and aggressive surgical intervention to untether the spinal cord is recommended before the onset of clinical deterioration.