Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thalamotomy for movement disorders

K J Burchiel1

  • 1Division of Neurosurgery, Oregon Health Sciences University, Portland 97201, USA.

Neurosurgery Clinics of North America
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Compensatory stepping in Parkinson's disease is still a problem after deep brain stimulation randomized to STN or GPi.

Journal of neurophysiology·2015
Same author

Psychological variables associated with outcome of spinal cord stimulation trials.

Neuromodulation : journal of the International Neuromodulation Society·2011
Same author

A meta-regression of the long-term effects of deep brain stimulation on balance and gait in PD.

Neurology·2010
Same author

Pathology of ilioinguinal neuropathy produced by mesh entrapment: case report and literature review.

Hernia : the journal of hernias and abdominal wall surgery·2007
Same author

Management of chronic severe pain: cerebral neuromodulatory and neuroablative approaches.

Acta neurochirurgica. Supplement·2007
Same author

Management of chronic severe pain: spinal neuromodulatory and neuroablative approaches.

Acta neurochirurgica. Supplement·2007
Same journal

Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Spinal Cord Deformities Associated with Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Radiation Therapy for Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Treatment Strategies of Intramedullary Spinal Cord Tumors.

Neurosurgery clinics of North America·2026
Same journal

Vascular Lesions of the Spinal Cord: Arteriovenous and Cavernous Malformations.

Neurosurgery clinics of North America·2026
Same journal

Hemangioblastomas of the Spinal Cord.

Neurosurgery clinics of North America·2026
See all related articles

Ventrolateral (VL) thalamotomy effectively controls tremors in various disorders, including Parkinson's disease and essential tremor. This stereotactic neurosurgery offers a safe and underutilized treatment option for movement disorders.

Area of Science:

  • Neurosurgery
  • Neurology
  • Stereotactic Surgery

Background:

  • Movement disorders like Parkinson's disease and essential tremor significantly impact quality of life.
  • Traditional treatments for tremor have limitations, leading to a need for effective surgical interventions.
  • Stereotactic neurosurgery has advanced with improved imaging and localization techniques.

Purpose of the Study:

  • To evaluate the efficacy and safety of ventrolateral (VL) thalamotomy for tremor control.
  • To discuss the indications and potential underutilization of thalamotomy.
  • To compare ablative surgery outcomes with emerging therapies like brain grafting.

Main Methods:

  • Review of clinical outcomes for VL thalamotomy in patients with movement disorders.

Related Experiment Videos

  • Analysis of indications including Parkinson's disease, essential tremor, and other tremor-generating conditions.
  • Consideration of morbidity associated with bilateral procedures and alternative therapies.

    • Main Results:

    • VL thalamotomy demonstrates excellent tremor control across a spectrum of neurological disorders.
    • While effective for Parkinson's disease symptoms like bradykinesia and rigidity, improvements are less pronounced than for hyperkinetic symptoms.
    • Morbidity is higher with bilateral lesions, suggesting caution for repeat procedures.

    Conclusions:

    • VL thalamotomy remains a highly effective and safe procedure for tremor management, despite potential underuse.
    • The technique is well-suited for specific indications and should be considered a primary treatment option.
    • While brain grafting is evolving, ablative surgery like thalamotomy currently offers superior results for select patient groups.