Role of gene amplification in drug resistance

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine.

Experimental eye research·2001

The degradation profile of extrachromosomal circular DNA during cisplatin-induced apoptosis is consistent with preferential cleavage at matrix attachment regions.

Chromosoma·1999

Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells.

Breast cancer research and treatment·1999

Fractionated ionizing radiation accelerates loss of amplified MDR1 genes harbored by extrachromosomal DNA in tumor cells.

Cancer research·1998

Efficient transduction of human hematopoietic cells with the human multidrug resistance gene 1 via SV40 pseudovirions.

Human gene therapy·1998

Enhanced potency of daunorubicin against multidrug resistant subline KB-ChR-8-5-11 by a pulsed magnetic field.

Anticancer research·1997

Clinical Trials and Translational Advances in Metabolic Targeting.

Cancer treatment and research·2026

Tools and Technologies for Studying Cancer Metabolism.

Cancer treatment and research·2026

Cancer and Immune Cells: A Metabolic Battle in the Tumor Microenvironment.

Cancer treatment and research·2026

Biomarkers of Cancer Metabolism and Therapeutic Response.

Cancer treatment and research·2026

Targeting Metabolism in Cancer Therapy: Inhibitors and Approaches.

Cancer treatment and research·2026

Metabolic Reprogramming in Cancer Stem Cells.

Cancer treatment and research·2026

A single-center retrospective study evaluating the efficacy of anlotinib plus temozolomide for recurrent glioma based on real-world data.

Translational cancer research·2026

Mechanism of miR-188-5p enhancing radioresistance in nasopharyngeal carcinoma by targeting PTEN to activate the PI3K/Akt signaling pathway.

Translational cancer research·2026

A real-world feasibility and safety study of anlotinib monotherapy in heavily pretreated or temozolomide-ineligible recurrent malignant glioma.

Translational cancer research·2026

Remodeling the tumor immune microenvironment: mechanisms of crosstalk between regulated cell death macrophages.

Frontiers in immunology·2026

Stem cell-derived exosomes preserve diabetic islet function: a systematic review and meta-analysis of preclinical studies.

Biophysics reports·2026

Pathological role of deubiquitinating enzymes in lung cancer: recent insights and advances.

American journal of cancer research·2026

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Role of gene amplification in drug resistance

Related Concept Videos

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine.

The degradation profile of extrachromosomal circular DNA during cisplatin-induced apoptosis is consistent with preferential cleavage at matrix attachment regions.

Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells.

Fractionated ionizing radiation accelerates loss of amplified MDR1 genes harbored by extrachromosomal DNA in tumor cells.

Efficient transduction of human hematopoietic cells with the human multidrug resistance gene 1 via SV40 pseudovirions.

Enhanced potency of daunorubicin against multidrug resistant subline KB-ChR-8-5-11 by a pulsed magnetic field.

Clinical Trials and Translational Advances in Metabolic Targeting.

Tools and Technologies for Studying Cancer Metabolism.

Cancer and Immune Cells: A Metabolic Battle in the Tumor Microenvironment.

Biomarkers of Cancer Metabolism and Therapeutic Response.

Targeting Metabolism in Cancer Therapy: Inhibitors and Approaches.

Metabolic Reprogramming in Cancer Stem Cells.

A single-center retrospective study evaluating the efficacy of anlotinib plus temozolomide for recurrent glioma based on real-world data.

Mechanism of miR-188-5p enhancing radioresistance in nasopharyngeal carcinoma by targeting PTEN to activate the PI3K/Akt signaling pathway.

A real-world feasibility and safety study of anlotinib monotherapy in heavily pretreated or temozolomide-ineligible recurrent malignant glioma.

Remodeling the tumor immune microenvironment: mechanisms of crosstalk between regulated cell death macrophages.

Stem cell-derived exosomes preserve diabetic islet function: a systematic review and meta-analysis of preclinical studies.

Pathological role of deubiquitinating enzymes in lung cancer: recent insights and advances.

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Role of gene amplification in drug resistance

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