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Vicryl (polyglactin 910) in cataract surgery. A controlled trial
The British Journal of Ophthalmology
|July 1, 1976
Summary
A new synthetic absorbable suture, Vicryl, showed a higher incidence of early complications in cataract surgery compared to traditional sutures. However, these differences were not statistically significant, suggesting Vicryl may be useful with technique modifications.
Area of Science:
- Ophthalmology
- Surgical Materials Science
Background:
- Cataract surgery commonly uses non-absorbable sutures like monofilament nylon or virgin silk.
- The development of synthetic absorbable sutures offers potential advantages in wound closure.
Purpose of the Study:
- To compare the safety and handling characteristics of a new synthetic absorbable suture (8-0 monofilament Vicryl) with conventional sutures in cataract operations.
- To evaluate early postoperative complications and intraoperative handling properties.
Main Methods:
- A controlled, randomized trial involving 45 cataract operations.
- Comparison of 8-0 monofilament Vicryl against 10-0 monofilament nylon and 8-0 virgin silk.
- Assessment of early complications (hyphaema, shallow anterior chamber, choroidal detachment) and suture handling qualities, including knot-tying.
Main Results:
- A higher incidence of early complications (15.4%) was observed with Vicryl compared to 0% with conventional sutures, though not statistically significant (p>0.05).
- Vicryl demonstrated superior handling qualities to nylon and silk, except for knot-tying, where it was inferior to virgin silk.
Conclusions:
- The synthetic absorbable suture Vicryl is a potentially useful option for cataract surgery.
- Further experience and modification of knot-tying techniques may mitigate the observed early complications.