Adverse reactions to therapy for HIV infection

Although chronic drug therapy with antiretroviral agents and chemoprophylaxis has led to longer survival without disease, high rates of adverse reactions to agents used to treat HIV infection have been reported. The incidence of adverse drug reactions in patients with HIV infection varies with the type of drug therapy, dosage, drug-to-drug interactions, and the stage of HIV infection. This article discusses recognition, treatment, and prevention of adverse reactions to specific drugs and classifications of drugs.