Related Experiment Videos
Lupus cystitis. report of a case
Y Takezawa1, N Ohtake, K Nakano
1Department of Urology, Tone Chuo Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|August 1, 1994
Summary
Systemic lupus erythematosus (SLE) can cause lupus cystitis, leading to bladder wall thickening and urinary tract issues. Prompt steroid treatment improved symptoms and imaging, though ureteral stenosis required stenting.
Area of Science:
- Nephrology
- Rheumatology
- Urology
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
- Urinary tract involvement in SLE can include cystitis, hydronephrosis, and hydroureters, complicating patient management.
- Lupus cystitis, characterized by bladder wall inflammation, is a rare but significant complication of SLE.
Observation:
- A 42-year-old female with SLE presented with anorexia and diagnosed hydronephrosis.
- Imaging revealed bilateral hydronephrosis, hydroureters, ascites, and thickened bladder/intestinal walls.
- Biopsy confirmed interstitial edema, fibrosis, and inflammation; cystometry was normal.
Findings:
- Diagnosis of lupus cystitis was established, and treatment with prednisolone initiated.
- Prednisolone therapy led to amelioration of anemia and reduced bladder/intestinal wall thickening.
- While left hydronephrosis improved, right ureteral stenosis worsened, necessitating stent insertion for relief.
Implications:
- This case highlights the importance of considering lupus cystitis in SLE patients with urinary symptoms.
- Early diagnosis and immunosuppressive therapy are crucial for managing lupus cystitis and its complications.
- Ureteral stenosis may require interventional procedures like stenting, even with effective medical treatment.