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Axis determination. Proteolytic generation of a morphogen
1Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, New Jersey 08544.
Current Biology : CB
|August 1, 1994
Abstract:
Ventral activation of a transmembrane receptor, Toll, is a crucial step in dorsoventral axis establishment in Drosophila embryos. The ventral ligand for Toll seems to be a proteolytic fragment of the Spätzle protein.