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[Cat-scratch disease and bacillary angiomatosis. An old and a new infectious disease with common etiology?]

K Engbaek1, W Frederiksen

  • 1Statens Seruminstitut, København, immunologisk udviklingsafdeling.

Ugeskrift for Laeger
|October 17, 1994
PubMed

Insights

Cat-scratch disease (CSD) and bacillary angiomatosis (BA) are reviewed, with Rochalimaea henselae and Afipia felis identified as key bacteria. Diagnosis and treatment options for these bacterial infections are discussed.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Bacteriology

Context:

  • Cat-scratch disease (CSD) and bacillary angiomatosis (BA) are reviewed based on published literature.
  • Two novel bacteria, Rochalimaea henselae and Afipia felis, have been isolated from CSD patients.
  • Afipia felis is preliminarily suggested as a less common cause of CSD.

Purpose:

  • To review cat-scratch disease (CSD) and bacillary angiomatosis (BA).
  • To discuss the pathological presentations, differential diagnoses, and diagnostic methods for CSD and BA.
  • To evaluate various diagnostic techniques, including bacterial visualization, isolation, genetic methods, and antibody detection, and to discuss treatment options.

Summary:

  • CSD can manifest as localized lymphadenopathy or systemic infection.
  • Bacillary angiomatosis (BA) is caused by Rochalimaea species and presents as angiomas or bacteremia, potentially as a manifestation of CSD in immunocompromised individuals.
  • Diagnostic approaches include Warthin-Starry silver impregnation, bacterial isolation, gene techniques, and serological antibody detection.

Impact:

  • Provides a comprehensive overview of CSD and BA, aiding clinicians in diagnosis and management.
  • Highlights the role of Rochalimaea henselae and Afipia felis in these diseases.
  • Discusses the spectrum of clinical presentations and diagnostic modalities for effective patient care.

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