Chemotherapy after hepatic resection of colorectal metastases

Although it is excepted practice now that one to three hepatic metastases from colorectal primaries should be resected, it is not clear whether treatment with chemotherapy, either via the hepatic artery or a systemic vein, is necessary after resection. There is some evidence that intraarterial therapy may decrease the incidence of hepatic recurrences but we must wait for the completion of the intergroup trial on postoperative therapy before a definitive answer can be made for the use of intraarterial therapy after hepatic resection.