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Systemic toxicity and dermal irritation of Tołpa Peat Preparation
H Czyzewska-Szafran1, Z Jastrzebski, D Sołtysiak-Pawluczuk
1Department of Pharmacology, Drug Institute, Warsaw, Poland.
Acta Poloniae Pharmaceutica
|January 1, 1993
Abstract:
The systemic toxicity of the peat preparation in rats and rabbits was assessed. Dermal irritation tests were conducted on rabbits. In acute and chronic toxicity studies TPP was well tolerated in both animal species. Laboratory findings revealed no hematologic abnormalities as well as disturbances in liver and kidney function. No local irritancy of TPP was found. The results show that TPP may be considered as practically non toxic.