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[Pulmonary involvement in primary Sjogren syndrome]
J M González Ruiz1, J L García-Satue, S Díaz Lobato
1Servicio de Neumología, Hospital General La Paz, Madrid.
Anales De Medicina Interna (Madrid, Spain : 1984)
|May 1, 1994
Summary
Primary Sjögren's Syndrome (PSS) often involves lung issues. Bronchoalveolar lavage and transbronchial biopsy can detect early pulmonary pathology in PSS patients.
Area of Science:
- Rheumatology
- Pulmonology
- Pathology
Context:
- Primary Sjögren's Syndrome (PSS) is an autoimmune disease affecting exocrine glands.
- Pulmonary involvement is a known complication of PSS, but early detection methods require further investigation.
Purpose:
- To document pulmonary involvement in PSS patients using bronchoalveolar lavage (BAL), transbronchial biopsy (TBBx), and respiratory functional assessment.
- To investigate the relationship between observed pulmonary pathology and specific diagnostic findings.
Summary:
- Six PSS patients were evaluated for pulmonary affection.
- All patients exhibited lymphocytic alveolitis via BAL, irrespective of radiological or functional findings.
- No correlation was found between alveolitis and histological results from TBBx.
Impact:
- BAL and TBBx are valuable tools for identifying early-stage lung disease in PSS.
- This study highlights the utility of invasive procedures in diagnosing subclinical pulmonary pathology in PSS.
- Findings contribute to a better understanding of the respiratory manifestations of PSS.