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Interleaved echo planar imaging on a standard MRI system

K Butts1, S J Riederer, R L Ehman

  • 1Magnetic Resonance Laboratory, Mayo Clinic, Rochester, Minnesota 55905.

Magnetic Resonance in Medicine
|January 1, 1994
PubMed
Summary
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A new interleaved echo planar imaging (EPI) method enhances signal-to-noise ratio on standard MRI scanners. This technique improves contrast for abdominal imaging and functional brain scans without complex adjustments.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Imaging Technology

Background:

  • Standard echo planar imaging (EPI) systems often have limitations in signal-to-noise ratio (SNR) and require specific adjustments.
  • Dedicated EPI systems may necessitate complex implementation and post-processing for optimal results.

Purpose of the Study:

  • To introduce and evaluate an interleaved EPI method adaptable to standard whole-body MRI scanners.
  • To assess the benefits of interleaved EPI in terms of SNR, image quality, and applicability to abdominal and functional imaging.

Main Methods:

  • The interleaved EPI method divides data acquisition into multiple repetitions (2-8) compared to conventional 1-2 repetitions.
  • This approach allows for a lower sampling bandwidth, leading to increased SNR.
  • The method was applied to breathhold T2-weighted abdominal imaging and functional MRI (fMRI).

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Main Results:

  • Interleaved EPI demonstrated a 1.21-fold increase in liver-lesion contrast compared to conventional spin-echo imaging in a 35-patient study.
  • Contrast-to-noise ratio (CNR) measurements showed interleaved EPI to be comparable to conventional spin-echo imaging (relative factor of 1.00).
  • An eight-shot interleaved EPI sequence successfully generated 128x128 images of cerebral activation during functional tasks.

Conclusions:

  • The interleaved EPI method offers a practical approach to enhance MRI imaging on standard scanners.
  • This technique provides improved contrast and comparable CNR for abdominal and functional imaging applications.
  • The method simplifies implementation by eliminating the need for distortion correction and case-by-case shimming.