Chemical models and chemotherapy in the sphingolipidoses

Apoptotic death by ceramide: will the real killer please stand up?

Medical hypotheses·2001

Treating glucosphingolipid disorders by chemotherapy: use of approved drugs and over-the-counter remedies.

Journal of inherited metabolic disease·2001

Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

European journal of biochemistry·2001

Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells.

British journal of cancer·1999

Chemotherapy by slowing glucosphingolipid synthesis.

Biochemical pharmacology·1999

Effect of an inhibitor of glucosylceramide synthesis on cultured human keratinocytes.

The Journal of dermatology·1998

Nucleoskeletal Proteins in Early Embryogenesis.

Advances in experimental medicine and biology·2026

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Advances in experimental medicine and biology·2026

Histone Modifications in Mammalian Early Embryos.

Advances in experimental medicine and biology·2026

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Advances in experimental medicine and biology·2026

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Advances in experimental medicine and biology·2026

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

Advances in experimental medicine and biology·2026

[Modern Methods of Molecular Modeling of Aptamers].

Molekuliarnaia biologiia·2026

Structure-Affinity Relationship Optimization of SYA16263 Yields New Ligands with Improved Receptor Affinity and Antipsychotic-Like Properties.

ACS omega·2026

Integrated in vivo and in silico validation of Corchorus olitorius seed-mediated cardioprotection against doxorubicin-induced cardiotoxicity via network pharmacology, molecular docking, and molecular dynamics.

Frontiers in chemistry·2026

Structure of an inhibitor bound to the catalytically important divalent metal ion site of afRioK1.

Journal of structural biology·2026

Heterometallic palladium(II) complexes as multi-targeting anticancer agents: Synthesis and investigation of the putative mechanism of action.

European journal of medicinal chemistry·2026

Computational and artificial intelligence-guided discovery of potential therapeutic candidates targeting Ml0099 protein of Mycobacterium leprae.

Computational biology and chemistry·2026

Related Experiment Videos

Chemical models and chemotherapy in the sphingolipidoses

Related Concept Videos

Apoptotic death by ceramide: will the real killer please stand up?

Treating glucosphingolipid disorders by chemotherapy: use of approved drugs and over-the-counter remedies.

Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells.

Chemotherapy by slowing glucosphingolipid synthesis.

Effect of an inhibitor of glucosylceramide synthesis on cultured human keratinocytes.

Nucleoskeletal Proteins in Early Embryogenesis.

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Histone Modifications in Mammalian Early Embryos.

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

[Modern Methods of Molecular Modeling of Aptamers].

Structure-Affinity Relationship Optimization of SYA16263 Yields New Ligands with Improved Receptor Affinity and Antipsychotic-Like Properties.

Integrated in vivo and in silico validation of Corchorus olitorius seed-mediated cardioprotection against doxorubicin-induced cardiotoxicity via network pharmacology, molecular docking, and molecular dynamics.

Structure of an inhibitor bound to the catalytically important divalent metal ion site of afRioK1.

Heterometallic palladium(II) complexes as multi-targeting anticancer agents: Synthesis and investigation of the putative mechanism of action.

Computational and artificial intelligence-guided discovery of potential therapeutic candidates targeting Ml0099 protein of Mycobacterium leprae.

Related Experiment Videos

Chemical models and chemotherapy in the sphingolipidoses

Related Concept Videos

Related Articles