Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunological tests in autoimmune rheumatic disease

D A Isenberg1

  • 1Bloomsbury Rheumatology Unit, London.

British Journal of Hospital Medicine
|September 5, 1993
PubMed
Summary

Autoantibodies are key indicators of autoimmune diseases but require clinical context for accurate interpretation. This review focuses on clinically significant autoantibodies in rheumatic diseases and introduces autoantibody disease imprinting.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cost of care of systemic lupus erythematosus (SLE) in the UK: annual direct costs for adult SLE patients with active autoantibody-positive disease.

Lupus·2013
Same author

Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus--report of 17 cases and review of the literature.

Lupus·2013
Same author

Heart failure in a woman with SLE, anti-phospholipid syndrome and Fabry's disease.

Lupus·2013
Same author

Cancer complicating systemic lupus erythematosus--a dichotomy emerging from a nested case-control study.

Lupus·2013
Same author

Rheumatological manifestations occurring in patients with diabetes mellitus.

Scandinavian journal of rheumatology·2012
Same author

What constitutes uncertainty in systemic lupus erythematosus and rheumatoid arthritis?

Psychology & health·2012

Area of Science:

  • Immunology
  • Rheumatology

Background:

  • Autoantibodies are critical diagnostic markers for autoimmune diseases.
  • However, their presence alone is not always definitive for diagnosis.
  • Clinical correlation is essential for accurate interpretation of autoantibody testing.

Purpose of the Study:

  • To review clinically relevant autoantibodies in autoimmune rheumatic diseases.
  • To introduce the concept of autoantibody disease imprinting.

Main Methods:

  • Literature review of autoantibodies in rheumatic diseases.
  • Conceptual framework for autoantibody disease imprinting.

Main Results:

  • Highlights key autoantibodies with diagnostic and prognostic value in rheumatic conditions.
  • Explains how autoantibody profiles can reflect disease development and progression.

Conclusions:

  • Autoantibody interpretation must integrate clinical history for precise diagnosis.
  • Autoantibody disease imprinting offers a novel perspective on understanding autoimmune disease pathogenesis.

Related Experiment Videos