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Pro- and anti-inflammatory cytokines in primary systemic vasculitis
J Kekow1, C H Szymkowiak, M Sticherling
1Department of Clinical Rheumatology, Medical University at Lübeck, Germany.
Advances in Experimental Medicine and Biology
|January 1, 1993
Abstract:
The expression of cytokines that are potentially involved in the pathogenesis of vasculitis was studied in patients with primary systemic vasculitis (PSV). In extension of earlier reports, we detected an overexpression of transforming growth factor beta (TGF beta), interleukin 6 (IL6), and interleukin 8 (IL8), indicating that the whole cytokine cascade is activated to a significant extent in PSV.