[Clinical features of primary chronic angle-closure glaucoma]

Area of Science:

• Ophthalmology
• Glaucoma Research
• Anterior Segment Imaging

Background:

• Primary chronic angle-closure glaucoma (PCACG) and primary acute angle-closure glaucoma (PAACG) are distinct entities.
• Understanding the differences in anterior segment biometry is crucial for diagnosis and management.

Purpose of the Study:

• To compare the ultrasonic biometry and anterior chamber angle width between PCACG, PAACG, and normal eyes.
• To investigate the clinical manifestations, natural course, and pathogenesis of PCACG.
• To establish diagnostic criteria and treatment principles for PCACG.

Main Methods:

• Ultrasonic biometry (anterior chamber depth, lens thickness, axial length) was performed on 43 PCACG eyes, 44 PAACG eyes, and 30 normal eyes.
• Anterior chamber angle width was measured using a slip-lamp micrometer.
• Clinical manifestations and dynamic changes in aqueous outflow were investigated in PCACG cases.

Main Results:

• Significant differences in anterior segment biometric parameters were observed between PCACG, PAACG, and normal eyes.
• Early-stage PCACG cases treated with miotics and/or peripheral iridectomy showed prevention of peripheral anterior synechiae (PAS) and disease progression.
• The study differentiated PCACG from minor attacks or progressive stages of PAACG.

Conclusions:

• Biometric differences in the anterior segment are key distinguishing features of PCACG.
• Timely intervention with miotics and/or peripheral iridectomy is effective in managing early PCACG and preventing complications.
• Clear diagnostic criteria and treatment principles for PCACG were established, emphasizing differentiation from PAACG.