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Long-term visual outcome and complications associated with pars planitis
S M Malinowski1, J S Pulido, J C Folk
1Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City.
Ophthalmology
|June 1, 1993
Summary
Pars planitis patients have a favorable visual prognosis, but complications like cataracts increase retinal detachment risk. Periphlebitis at diagnosis elevates the risk of optic neuritis or multiple sclerosis (MS).
Area of Science:
- Ophthalmology
- Neurology
- Immunology
Background:
- Pars planitis is an idiopathic inflammatory condition affecting the intermediate uvea.
- Ocular complications and potential systemic associations require further investigation.
Purpose of the Study:
- To identify ocular complications in pars planitis patients.
- To evaluate the association between pars planitis and multiple sclerosis (MS).
Main Methods:
- Retrospective review of 54 patients (108 eyes) with idiopathic pars planitis.
- Analysis of ocular complications, visual acuity changes, and development of MS or optic neuritis.
Main Results:
- Favorable visual acuity outcomes observed over mean follow-up of 89.2 months.
- Common complications included cataracts (14.8%), CME (8.3%), and retinal detachment (8.3%).
- 14.8% developed MS, and 7.4% developed optic neuritis; periphlebitis increased this risk (P=0.002).
Conclusions:
- Pars planitis generally has a favorable visual prognosis.
- Cataract formation is linked to increased retinal detachment risk.
- A strong association between pars planitis and MS is confirmed, suggesting a shared etiology.