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[Features of ethmozine metabolism]
Farmakologiia I Toksikologiia
|January 1, 1977
Abstract:
A study of the aethozine metabolism in the urine of rats detected 14 metabolites, a number of which was identified, namely: 2-aminophenothiazine, 2-acetylamide-phenothiazine, ethyl ether of phenothiazine-carbamine-2-acid, their sulphoxides and also aethmozine sulphoxide. Of the aethmozine biotransformation processes is characteristic formation in the organism of the animals of significant quantities of transformation products with complete degradation of the side chain.