Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Blood relationship]

U Theile1, S Hoffmann

  • 1Genetische Beratungsstelle Rheinland-Pfalz, Mainz.

Therapeutische Umschau. Revue Therapeutique
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

Consanguinity between parents increases the risk of hereditary diseases in children, particularly autosomal recessive disorders. Genetic counseling is crucial for assessing these risks, especially in cases of rare genetic conditions or isolated populations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Crash localization and traffic impact assessment via spatio-temporal analysis of connected vehicle data.

Accident; analysis and prevention·2025
Same author

Severe COVID-19 and its cardiopulmonary effects 6 and 18 months after hospital discharge.

Frontiers in cardiovascular medicine·2024
Same author

Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control.

Biochimica et biophysica acta. Gene regulatory mechanisms·2021
Same author

Treating patients with driving phobia by virtual reality exposure therapy - a pilot study.

PloS one·2020
Same author

Biomarkers of immune capacity, infection and inflammation are associated with poor outcome and mortality after stroke - the PREDICT study.

BMC neurology·2019
Same author

Isolated impact of liver herniation on outcome in fetuses with congenital diaphragmatic hernia - A matched-pair analysis based on fetal MRI relative lung volume.

European journal of radiology·2018
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Non-invasive diagnostic imaging for coronary artery disease: choosing the right test for the right patient].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodality imaging in the diagnostic work-up in patients with heart failure in clinical practice].

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Area of Science:

  • Medical Genetics
  • Human Genetics
  • Population Genetics

Context:

  • Consanguinity is rarely considered in routine medical practice.
  • It becomes relevant for genetic counselors and pediatricians when diagnosing rare hereditary disorders or assessing parental risks.
  • Isolated ethnic or social groups may also exhibit a higher prevalence of certain genetic disorders.

Purpose:

  • To detail the genetic implications of consanguinity in offspring.
  • To explain how parental relatedness influences the inheritance of genetic diseases.
  • To highlight the role of genetic counseling in managing hereditary risks.

Summary:

  • Parental consanguinity, including first or second-degree cousin relationships, increases the probability of offspring inheriting homozygous genetic disorders.

Related Experiment Videos

  • Autosomal recessive disorders are particularly relevant, as consanguinity can explain unexpected diagnoses and increase recurrence risks for siblings.
  • Incestuous conception presents a significant genetic risk, requiring careful consideration in adoption and family planning.

    • Impact:

    • Provides a framework for understanding and calculating genetic risks associated with consanguineous unions.
    • Informs genetic counseling strategies for families with a history of hereditary diseases.
    • Emphasizes the importance of considering parental relatedness and population genetics in diagnosing and managing genetic conditions.