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Radiological evidence of constipation in urinary tract infection
A J Blethyn1, H R Jenkins, R Roberts
1Department of Radiology, University Hospital of Wales, Cardiff.
Constipation, indicated by increased fecal loading, is associated with recurrent urinary tract infections (UTIs) in children, particularly girls. Further research is needed to confirm a causal link and treatment benefits.
Area of Science:
- Pediatric Nephrology
- Pediatric Gastroenterology
- Radiology
Background:
- Recurrent urinary tract infections (UTIs) are a common childhood issue.
- The link between constipation and recurrent UTIs in children lacks substantial objective evidence.
- Constipation may contribute to UTIs through various mechanisms, including rectal-urinary tract proximity and bacterial translocation.
Purpose of the Study:
- To investigate the association between fecal loading and recurrent urinary tract infections (UTIs) in children.
- To determine if constipation is a significant factor in childhood recurrent UTIs.
Main Methods:
- Abdominal radiographs of children with confirmed UTIs were assessed for fecal loading using a standardized radiological scoring system.
- Two independent observers evaluated the degree of fecal loading.
- A comparison was made between children with UTIs and a control group.
Main Results:
- A statistically significant increase in fecal loading was observed in children with UTIs compared to controls (r = 0.237).
- This association was primarily driven by girls experiencing frequent UTIs (more than five episodes).
Conclusions:
- The study confirms a significant association between increased fecal loading (constipation) and recurrent UTIs in children.
- Further investigation is warranted to establish a causal relationship and evaluate the potential benefits of constipation management in treating recurrent UTIs.
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