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Pancreaticoduodenectomy for benign disease
S A Barens1, K D Lillemoe, H S Kaufman
1Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
American Journal of Surgery
|January 1, 1996
Summary
Pancreaticoduodenectomy for benign disease shows low mortality (<1%) and manageable complications. This suggests an aggressive surgical approach is safe for carefully selected patients with benign pancreatic conditions.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Hepatobiliary Surgery
Background:
- Pancreaticoduodenectomy is performed for malignant and benign pancreatic diseases.
- Improved surgical techniques have reduced perioperative risks.
- Indications are expanding to include non-malignant conditions.
Purpose of the Study:
- To evaluate the safety and outcomes of pancreaticoduodenectomy for benign pancreatic diseases.
- To compare outcomes in patients with chronic pancreatitis versus other benign conditions.
Main Methods:
- Retrospective review of 108 patients undergoing pancreaticoduodenectomy for benign disease.
- Comparison of patients with chronic pancreatitis to those with other benign conditions.
Main Results:
- Mortality rate was less than 1%.
- Overall complication rate was 51%, with delayed gastric emptying being most common.
- Pancreatic anastomotic leak occurred in 18% and was more frequent in non-chronic pancreatitis benign diseases (31% vs 8%).
Conclusions:
- Pancreaticoduodenectomy for benign disease has low mortality and morbidity in selected patients.
- Concerns about risks should not deter aggressive surgical resection for benign conditions.
- Careful patient selection is crucial for optimal outcomes.