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Artificial chordae
1Department of Cardiac Surgery, Regional Hospital, Treviso, Italy.
The Journal of Heart Valve Disease
|October 1, 1995
Summary
This study demonstrates the safety and efficacy of using expanded polytetrafluoroethylene (e-PTFE) artificial chordae for mitral valve repair and replacement. The technique shows excellent long-term results and improves patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
Background:
- Mitral valve disease management often requires complex surgical interventions.
- Expanded polytetrafluoroethylene (e-PTFE) offers potential for durable artificial chordae in mitral valve procedures.
Purpose of the Study:
- To evaluate the long-term safety and efficacy of mitral valve repair and replacement using e-PTFE artificial chordae.
- To assess the functional outcomes and complication rates associated with this surgical technique.
Main Methods:
- Retrospective analysis of 215 patients undergoing mitral valve repair (187) or replacement (28) using e-PTFE artificial chordae.
- Mean of 6.7 artificial chordae per patient, often combined with autologous pericardium reinforced annuloplasty.
- Follow-up included clinical assessment, echocardiography, and review of complications and reoperations.
Main Results:
- One operative death; no early valve-related complications.
- At mean 35.6-month follow-up, 97% had satisfactory echocardiographic results.
- 95% of patients achieved NYHA class I; three reoperations for chordae rupture or disease progression.
Conclusions:
- Mitral valve repair/replacement with e-PTFE artificial chordae is reproducible and reliable.
- This technique improves mitral valve repair rates and optimizes left ventricular function.
- The artificial chordae showed no thrombosis or calcification at reoperation, suggesting good biocompatibility.