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Related Experiment Video

Updated: Jul 21, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Breast cancer in men

W L Donegan¹, P N Redlich

¹Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

The Surgical Clinics of North America

|April 1, 1996

Summary

Male breast cancer shares similarities with female breast cancer, though it occurs less frequently. Early detection and treatment, including surgery and adjuvant therapy, are crucial for a positive prognosis in male patients.

Area of Science:

Oncology
Men's Health

Background:

Male breast cancer is rare but shares significant similarities with female breast cancer in presentation, pathology, and natural history.
The etiology of breast cancer in men remains largely unknown.

Purpose of the Study:

To compare the characteristics and outcomes of male breast cancer with those in women.
To highlight key prognostic factors and treatment modalities for male breast cancer.

Main Methods:

Review of clinical presentation, pathology, and natural history of male breast cancer.
Analysis of diagnostic and prognostic indicators, including tumor stage and axillary node status.
Evaluation of surgical and systemic adjuvant therapy approaches.

Main Results:

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Published on: February 6, 2019

Male breast cancer is often diagnosed at older ages and more advanced stages compared to women.
Tumors in men are frequently located retroareolar and show responsiveness to hormonal therapy.
Stage and axillary lymph node status are critical prognostic indicators.
Modified radical mastectomy is the preferred surgical approach for early-stage disease.

Conclusions:

Male breast cancer is clinically and pathologically similar to female breast cancer, with comparable curability under similar circumstances.
Systemic adjuvant therapy can improve prognosis in male patients with lymph node involvement.
Further research into the causes and specific treatments for male breast cancer is warranted.