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In vitro fertilization in a spontaneous cycle: a successful simple protocol
M A Aboulghar1, R T Mansour, G A Serour
1Department of Obstetrics and Gynecology, Cairo University, Egypt.
Journal of Obstetrics and Gynaecology (Tokyo, Japan)
|August 1, 1995
Summary
This study shows that in vitro fertilization (IVF) in a natural cycle is a safe and cost-effective treatment for infertility. It offers a reasonable pregnancy rate for young women with tubal factors.
Area of Science:
- Reproductive Medicine
- Infertility Treatment
- Assisted Reproductive Technology
Background:
- Natural cycle in vitro fertilization (IVF) offers a simpler approach to infertility treatment.
- Tubal factor infertility affects women seeking assisted reproductive technologies.
Purpose of the Study:
- To evaluate the efficacy of a simplified in vitro fertilization protocol.
- To assess the outcomes of natural cycle IVF for tubal factor infertility.
Main Methods:
- Prospective study of natural cycle IVF in women with tubal infertility.
- Monitoring via vaginal ultrasound and urinary luteinizing hormone (LH).
- Tracking cycle cancellations, oocyte retrieval, embryo transfer, and pregnancy rates.
Main Results:
- Cycle cancellation occurred in 49.8% due to early LH surge or follicular development issues.
- Oocyte retrieval rate was 87.5% in cycles with pick-up.
- Pregnancy rate per pick-up was 10.2% with no pregnancy wastage.
Conclusions:
- Natural cycle IVF is a simple, low-cost, and safe infertility treatment.
- It provides a reasonable pregnancy rate for young women with tubal infertility.
- This method is suitable for regularly menstruating women with specific infertility causes.