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The relationship between in vitro and in vivo venous compliance measurement
P Zamboni1, M G Marcellino, F Portaluppi
1Department of Surgery and Vascular Laboratory, University of Ferrara, Italy.
Objective:
To assess the relationship between in vitro and in vivo venous compliance measurement.
Design:
Prospective, blind study.
Materials And Methods:
Patients affected by primary varicose veins and classified in accord with the new CEAP criteria (C2-6/S, Ep, AS1-4/p17-18, PR) underwent blind venous compliance measurements using two different methods. 1) In vivo assessment of the compliance of the greater saphenous vein by duplex scanning, for diameter, and a needle transducer, for venous pressure measurements. 2) In vitro standard compliance assessment of the same vein segment after its excision.
Results:
The compliance values obtained with the two methods showed a significant degree of correlation, which improved with increasing intravenous pressures.
Conclusions:
In vivo compliance assessment of the saphenous vein was validated by the relationship with the standard in vitro measurement.