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The new colitides, Collagenous, lymphocytic, and diversion colitis
F M Giardiello1, A J Lazenby, T M Bayless
1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gastroenterology Clinics of North America
|September 1, 1995
Summary
This study discusses three types of colitis: collagenous, lymphocytic, and diversion colitis. It details their clinical and histologic features, focusing on chronic watery diarrhea and surgical alterations of the large intestine.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Histopathology
Background:
- Collagenous and lymphocytic colitis are inflammatory bowel disorders presenting with chronic watery diarrhea.
- These conditions affect middle-aged individuals and have unknown etiologies.
- Diversion colitis arises from surgical exclusion of large intestine segments from fecal flow.
Purpose of the Study:
- To describe the clinical and histologic features of collagenous, lymphocytic, and diversion colitis.
- To differentiate these three distinct colitis entities.
- To provide an overview of their presentation and underlying mechanisms.
Main Methods:
- Review of clinical presentations of patients with these colitides.
- Histopathologic examination of colonic biopsies.
- Analysis of surgical cases leading to diversion colitis.
Main Results:
- Collagenous and lymphocytic colitis share similarities in presentation and unknown cause.
- Diversion colitis is characterized by specific histologic changes secondary to fecal diversion.
- Distinct clinical and microscopic findings differentiate these colitides.
Conclusions:
- Collagenous, lymphocytic, and diversion colitis are distinct entities with unique features.
- Understanding these features is crucial for accurate diagnosis and management.
- Further research into the etiology of collagenous and lymphocytic colitis is warranted.