Anaesthesia for patients with trisomy 13 (Patau's syndrome)

Area of Science:

• Pediatric Anesthesiology
• Medical Genetics
• Surgical Neonatology

Background:

• Patau's syndrome (Trisomy 13) is a rare chromosomal disorder with a high mortality rate, typically within the first six months of life.
• Surgical interventions for survivors are infrequent due to the condition's severity and limited long-term prognosis.
• Anesthetic and surgical case reports for Patau's syndrome are exceptionally rare in medical literature.

Observation:

• This study presents two pediatric cases of Patau's syndrome requiring surgical intervention.
• The cases involved anesthesia management for corrective surgery of cleft lip and palate defects.
• The department managed the anesthetic care for these two specific patients.

Findings:

• Successful anesthesia was administered for cleft lip and palate repair in two children diagnosed with Patau's syndrome.
• The report documents the anesthetic procedures and considerations for these rare surgical cases.
• This contributes to the limited existing literature on surgical management in Trisomy 13 survivors.

Implications:

• Highlights the feasibility of surgical correction, such as cleft lip and palate repair, in select Trisomy 13 patients.
• Provides valuable insights for anesthesiologists and surgical teams managing rare pediatric genetic disorders.
• Emphasizes the importance of individualized care and risk assessment in Patau's syndrome cases requiring medical or surgical intervention.