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[Effect of five fluoroquinolones on the bactericidal activity of human polymorphonuclear leukocytes against
S Ballesta1, A Pascual, I García
1Departamento de Microbiología, Facultad de Medicina, Universidad de Sevilla.
Enfermedades Infecciosas Y Microbiologia Clinica
|December 1, 1996
Abstract:
It has been evaluated the effect of norfloxacin, ofloxacin, levofloxacin, fleroxacin and lomefloxacin of the respiratory burst of human polymorphonuclear leukocytes and their intracellular activity against Staphylococcus aureus. None of these agents significantly affected the superoxide and hydrogen peroxide radicals production by the polymorphonuclear leukocytes. All the quinolones except norfloxacin showed significant intracellular activity against S. aureus.