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[RS3PE syndrome: presentation of two cases]
J V Parra Ródenas1, J Calvo Catalá, M I González-Cruz Cervellera
1Seccion de Reumatología y Osteoporosis, Hospital Universitario General, Valencia.
Anales De Medicina Interna (Madrid, Spain : 1984)
|December 1, 1996
Summary
The remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is an acute arthritis in elderly patients. This benign condition has an excellent prognosis and is distinct from other rheumatic diseases.
Area of Science:
- Rheumatology
- Geriatric Medicine
- Clinical Immunology
Background:
- The remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a recently described clinical entity.
- RS3PE syndrome is characterized by acute onset, symmetrical synovitis, pitting edema, and a predilection for elderly individuals.
- Distinguishing RS3PE from other inflammatory arthropathies like rheumatoid arthritis and polymyalgia rheumatica is clinically important.
Observation:
- RS3PE syndrome typically presents with acute onset synovitis.
- A key characteristic is pitting edema, particularly affecting the hands and feet.
- The condition shows a predilection for elderly patients.
Findings:
- RS3PE syndrome is distinguished by its symmetrical synovitis without producing bony erosions.
- Patients with RS3PE syndrome generally experience an excellent prognosis.
- The syndrome is seronegative, meaning rheumatoid factor and anti-CCP antibodies are typically absent.
Implications:
- This benign arthritis form in aging patients requires recognition to avoid misdiagnosis.
- Understanding RS3PE syndrome aids in providing appropriate and timely patient care.
- Further research into the pathogenesis and optimal treatment strategies for RS3PE syndrome is warranted.