[The immunological indices in pathology due to yersiniosis]

Immunological characteristics in the time course of infectious processes in pseudotuberculosis and yersiniosis were studied. In diseases caused by Y. pseudotuberculosis highly virulent strains, serovar I, the suppression of T-cell-mediated immunity and a decrease in the characteristics of nonspecific resistance, especially at the peak of the process, as well as the tardy production of specific antibodies, were observed. For the relapsing course of infection, less pronounced decrease of immunological characteristics, whose values remained low also at the period of expected convalescence, was established. The study of the immune status in yersiniosis showed differences in immunological characteristics, depending on the serovar of the infective agent. In comparison with yersiniosis caused by Y. enterocolitica, serovar O9, yersiniosis caused by Y. enterocolitica, serovar O3, was found to produce more profound disturbances in the immune system and to have the potential possibility for the development of autoimmune complications.