[Percutaneous transvenous balloon dilatation of mitral valve stenosis]

In this study, 42 consecutive symptomatic patients (median age 60 (30-78) years, 86% females) with mitral valve stenosis (57% had severely deformed and/or calcified mitral valves) were treated with (Inoue) balloon dilatation during the period August 1989-June 1994. Mitral valve area and cardiac output increased by 67 and 25%, whereas the transmital gradient as well as pulmonary artery pressure fell by 45% and 21%, respectively, after the dilatation. Follow-up at a mean of 16 (1-46) months revealed a total mortality of 12% (cardiac mortality of 7%). Five patients developed significant' mitral regurgitation after the treatment and four of these had subacute mitral valve replacement. A further four patients received an artificial valve during the follow-up period. During the follow-up period the increase in valve area remained unchanged, and accordingly 97% of the patients were in New York Heart Association functional class I-II. Balloon dilatation was an acceptable treatment in the described elderly population with significant mitral stenosis and deformed valves.