[Toxic shock-like syndrome caused by streptococci--treated with clindamycin]
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Updated: Nov 1, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
1Medicinsk afdeling, Sønderborg Sygehus.
Abstract:
The number of invasive group A streptococcal infections have been increasing in the last years. Toxic Shock-like Syndrome due to infections with streptococci (TSLS) is a serious condition still associated with a mortality rate of 30% despite proper treatment. Early diagnosis is difficult and early treatment is important. A typical case of TSLS in a previously healthy 33 year-old woman treated with clindamycin is reported. Penicillin is still the drug of choice for most Group A streptococcal infections, but in fulminant infections failure has been described. Clindamycin is a good choice in complicated infections.
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