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Updated: Aug 13, 2026

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Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
[Transurethral balloon laser thermotherapy for benign prostatic hyperplasia]
H Umeda1, Y Yoshimura, O Yamaguchi
1Department of Urology, Fukushima Medical College.
Hinyokika Kiyo. Acta Urologica Japonica
|June 1, 1997
Summary
Transurethral balloon laser thermotherapy (TUBAL-T) significantly improved subjective benign prostatic hyperplasia symptoms. However, objective measures of prostate health did not show significant changes post-treatment.
Area of Science:
- Urology
- Minimally Invasive Therapies
Background:
- Benign prostatic hyperplasia (BPH) is a common condition affecting aging men.
- Current BPH treatments include medication, surgery, and minimally invasive procedures.
- Transurethral balloon laser thermotherapy (TUBAL-T) is one such minimally invasive option.
Purpose of the Study:
- To evaluate the clinical efficacy of transurethral balloon laser thermotherapy (TUBAL-T) for benign prostatic hyperplasia (BPH).
- To assess changes in both subjective and objective parameters following TUBAL-T.
Main Methods:
- A cohort of 53 patients with BPH underwent TUBAL-T using Prostalase.
- Clinical efficacy was assessed at 3 months post-procedure.
- International Prostate Symptom Score (I-PSS) was used to evaluate subjective symptoms.
- Objective parameters included maximum flow rate, voided volume, postvoid residual volume, and prostate volume.
Main Results:
- Mean I-PSS significantly decreased from 21.5 to 11.3 (p < 0.0001).
- Irritative symptoms improved by 55% and obstructive symptoms by 45%.
- No significant changes were observed in maximum flow rate, voided volume, percent postvoid residual volume, or prostate volume.
Conclusions:
- TUBAL-T demonstrates significant improvement in subjective BPH symptoms, particularly irritative ones.
- Objective parameters related to urinary flow and prostate size did not show significant improvement.
- TUBAL-T may be an effective option for symptom relief in BPH patients, but its impact on objective measures requires further investigation.

